Is epidemiology ready for epigenetics?

Is epidemiology ready for epigenetics?

The revellers depicted in the painting by the Dutch artist Judith Leyster (1609–60) (Figure 1) will not have given epigenetics a passing thought. Little were they to know that indulgences, such as drinking alcohol and smoking, would be contributing to their ‘exposome’ and marking their epigenome to potentially compromise their future health. The skeleton proffering an hourglass is perhaps a por...

Commentary: The epidemiology of epigenetics.

of the conventional kind; one can make operations on the developing wings, using fine glass needles and the other micro-surgical instruments of experimental embryology. A considerable series of such operations has been made by Lees 6 who was able to confirm, and in some cases to extend, many of the previous deductions. For this particular organ there remains very little of that gap between gene...

vertical gastric plication: is it ready for prime-time?

Epigenetics, epidemiology and mitochondrial DNA diseases.

Over the last two decades, the mutation of mitochondrial DNA (mtDNA) has emerged as a major cause of inherited human disease. The disorders present clinically in at least 1 in 10,000 adults, but pathogenic mutations are found in approximately 1 in 200 of the background population. Mitochondrial DNA is maternally inherited and there can be marked phenotypic variability within the same family. He...

Is chiropractic ready for research?